Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains

Transmission of chronic wasting disease (CWD) between cervids is influenced by the primary structure of the host cellular prion protein (PrP(C)). In white-tailed deer, PRNP alleles encode the polymorphisms Q95 G96 (wild type [wt]), Q95 S96 (referred to as the S96 allele), and H95 G96 (referred to as...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Duque Velásquez, Camilo, Kim, Chiye, Herbst, Allen, Daude, Nathalie, Garza, Maria Carmen, Wille, Holger, Aiken, Judd, McKenzie, Debbie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Prions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665243/
https://ncbi.nlm.nih.gov/pubmed/26423950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02010-15
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