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Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP(CWD) deposition in orally infected white-tailed deer

BACKGROUND: Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrP(C) primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CWD strains. We analyzed the distribution of abnormal prio...

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書目詳細資料
發表在:BMC Vet Res
Main Authors: Otero, Alicia, Duque Velásquez, Camilo, Johnson, Chad, Herbst, Allen, Bolea, Rosa, Badiola, Juan José, Aiken, Judd, McKenzie, Debbie
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360794/
https://ncbi.nlm.nih.gov/pubmed/30717795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-1794-z
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