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White-tailed deer S96 prion protein does not support stable in vitro propagation of most common CWD strains
PrP(C) variation at residue 96 (G/S) plays an important role in the epidemiology of chronic wasting disease (CWD) in exposed white-tailed deer populations. In vivo studies have demonstrated the protective effect of serine at codon 96, which hinders the propagation of common CWD strains when expresse...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8160261/ https://ncbi.nlm.nih.gov/pubmed/34045540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90606-8 |
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