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Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains

Transmission of chronic wasting disease (CWD) between cervids is influenced by the primary structure of the host cellular prion protein (PrP(C)). In white-tailed deer, PRNP alleles encode the polymorphisms Q95 G96 (wild type [wt]), Q95 S96 (referred to as the S96 allele), and H95 G96 (referred to as...

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Bibliographic Details
Published in:J Virol
Main Authors: Duque Velásquez, Camilo, Kim, Chiye, Herbst, Allen, Daude, Nathalie, Garza, Maria Carmen, Wille, Holger, Aiken, Judd, McKenzie, Debbie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665243/
https://ncbi.nlm.nih.gov/pubmed/26423950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02010-15
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