Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrP(Sc) Accumulation

During prion infections of the central nervous system (CNS) the cellular prion protein, PrP(C), is templated to a conformationally distinct form, PrP(Sc). Recent studies have demonstrated that the Sprn gene encodes a GPI-linked glycoprotein Shadoo (Sho), which localizes to a similar membrane environ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Westaway, David, Genovesi, Sacha, Daude, Nathalie, Brown, Rebecca, Lau, Agnes, Lee, Inyoul, Mays, Charles E., Coomaraswamy, Janaky, Canine, Brenda, Pitstick, Rose, Herbst, Allen, Yang, Jing, Ko, Kerry W. S., Schmitt-Ulms, Gerold, DeArmond, Stephen J., McKenzie, Debbie, Hood, Leroy, Carlson, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219720/
https://ncbi.nlm.nih.gov/pubmed/22114562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002391
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados