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Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus
The Shadoo protein (Sho) exhibits homology to the hydrophobic region of the cellular isoform of prion protein (PrP(C)). As prion-infected brains gradually accumulate infectivity-associated isoforms of prion protein (PrP(Sc)), levels of mature endogenous Sho become reduced. To study the regulatory ef...
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| Pubblicato in: | Mol Neurobiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer US
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815274/ https://ncbi.nlm.nih.gov/pubmed/31129810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-1623-1 |
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