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Interaction between Shadoo and PrP Affects the PrP-Folding Pathway
Prion diseases are characterized by conformational changes of a cellular prion protein (PrP(C)) into a β-sheet-enriched and aggregated conformer (PrP(Sc)). Shadoo (Sho), a member of the prion protein family, is expressed in the central nervous system (CNS) and is highly conserved among vertebrates....
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474288/ https://ncbi.nlm.nih.gov/pubmed/25855735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03429-14 |
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