Interaction between Shadoo and PrP Affects the PrP-Folding Pathway

Prion diseases are characterized by conformational changes of a cellular prion protein (PrP(C)) into a β-sheet-enriched and aggregated conformer (PrP(Sc)). Shadoo (Sho), a member of the prion protein family, is expressed in the central nervous system (CNS) and is highly conserved among vertebrates....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ciric, Danica, Richard, Charles-Adrien, Moudjou, Mohammed, Chapuis, Jérôme, Sibille, Pierre, Daude, Nathalie, Westaway, David, Adrover, Miguel, Béringue, Vincent, Martin, Davy, Rezaei, Human
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Prions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474288/
https://ncbi.nlm.nih.gov/pubmed/25855735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03429-14
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