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Integrity of Helix 2-Helix 3 Domain of the PrP Protein Is Not Mandatory for Prion Replication
The process of prion conversion is not yet well understood at the molecular level. The regions critical for the conformational change of PrP remain mostly debated and the extent of sequence change acceptable for prion conversion is poorly documented. To achieve progress on these issues, we applied a...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365929/ https://ncbi.nlm.nih.gov/pubmed/22511770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341677 |
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