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Prion Propagation in Cells Expressing PrP Glycosylation Mutants
Infection by prions involves conversion of a host-encoded cell surface protein (PrP(C)) to a disease-related isoform (PrP(Sc)). PrP(C) carries two glycosylation sites variably occupied by complex N-glycans, which have been suggested by previous studies to influence the susceptibility to these diseas...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067877/ https://ncbi.nlm.nih.gov/pubmed/21248032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02257-10 |
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