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Prion Propagation in Cells Expressing PrP Glycosylation Mutants

Infection by prions involves conversion of a host-encoded cell surface protein (PrP(C)) to a disease-related isoform (PrP(Sc)). PrP(C) carries two glycosylation sites variably occupied by complex N-glycans, which have been suggested by previous studies to influence the susceptibility to these diseas...

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Sonraí Bibleagrafaíochta
Main Authors: Salamat, Muhammad K., Dron, Michel, Chapuis, Jérôme, Langevin, Christelle, Laude, Hubert
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067877/
https://ncbi.nlm.nih.gov/pubmed/21248032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02257-10
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