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Mammalian prion propagation in PrP transgenic Drosophila
Mammalian prions propagate by template-directed misfolding and aggregation of normal cellular prion related protein PrP(C) as it converts into disease-associated conformers collectively referred to as PrP(Sc). Mammalian species may be permissive for prion disease because these hosts have co-evolved...
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| Publié dans: | Brain |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6113635/ https://ncbi.nlm.nih.gov/pubmed/29985975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy183 |
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