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Mammalian prion propagation in PrP transgenic Drosophila

Mammalian prions propagate by template-directed misfolding and aggregation of normal cellular prion related protein PrP(C) as it converts into disease-associated conformers collectively referred to as PrP(Sc). Mammalian species may be permissive for prion disease because these hosts have co-evolved...

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Podrobná bibliografie
Vydáno v:Brain
Hlavní autoři: Thackray, Alana M, Andréoletti, Olivier, Bujdoso, Raymond
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113635/
https://ncbi.nlm.nih.gov/pubmed/29985975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy183
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