Genetic human prion disease modelled in PrP transgenic Drosophila

Inherited human prion diseases, such as fatal familial insomnia (FFI) and familial Creutzfeldt–Jakob disease (fCJD), are associated with autosomal dominant mutations in the human prion protein gene PRNP and accumulation of PrP(Sc), an abnormal isomer of the normal host protein PrP(C), in the brain o...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Thackray, Alana M., Cardova, Alzbeta, Wolf, Hanna, Pradl, Lydia, Vorberg, Ina, Jackson, Walker S., Bujdoso, Raymond
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606059/
https://ncbi.nlm.nih.gov/pubmed/28814578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170462
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires