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Genetic human prion disease modelled in PrP transgenic Drosophila
Inherited human prion diseases, such as fatal familial insomnia (FFI) and familial Creutzfeldt–Jakob disease (fCJD), are associated with autosomal dominant mutations in the human prion protein gene PRNP and accumulation of PrP(Sc), an abnormal isomer of the normal host protein PrP(C), in the brain o...
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| Publié dans: | Biochem J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Portland Press Ltd.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5606059/ https://ncbi.nlm.nih.gov/pubmed/28814578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170462 |
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