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Perturbation of T-cell development by insertional mutation of a PrP transgene

The normal cellular form of the prion protein PrP(C) is a glycosylphosphatidylinositol-linked cell-surface glycoprotein expressed primarily by cells of the nervous and immune systems. There is evidence to suggest that PrP(C) is involved in cell signalling and cellular homeostasis. We have investigat...

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Detalhes bibliográficos
Main Authors: Zabel, Mark, Greenwood, Christina, Thackray, Alana M, Pulford, Bruce, Rens, Willem, Bujdoso, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691788/
https://ncbi.nlm.nih.gov/pubmed/19143847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02944.x
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