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Molecular and Transmission Characteristics of Primary-Passaged Ovine Scrapie Isolates in Conventional and Ovine PrP Transgenic Mice

A more complete assessment of ovine prion strain diversity will be achieved by complementing biological strain typing in conventional and ovine PrP transgenic mice with a biochemical analysis of the resultant PrPSc. This will provide a correlation between ovine prion strain phenotype and the molecul...

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Autors principals: Thackray, Alana M., Hopkins, Lee, Spiropoulos, John, Bujdoso, Raymond
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573291/
https://ncbi.nlm.nih.gov/pubmed/18768980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01454-08
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