Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay

Por Thackray, Alana M., Hopkins, Lee, Bujdoso, Raymond
Publicado em 2006

Molecular and Transmission Characteristics of Primary-Passaged Ovine Scrapie Isolates in Conventional and Ovine PrP Transgenic Mice

Por Thackray, Alana M., Hopkins, Lee, Spiropoulos, John, Bujdoso, Raymond
Publicado em 2008

Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrP(C)

Por Thackray, Alana M., Fitzmaurice, Tim J., Hopkins, Lee, Bujdoso, Raymond
Publicado em 2006

Mouse-Adapted Ovine Scrapie Prion Strains Are Characterized by Different Conformers of PrPSc

Por Thackray, Alana M., Hopkins, Lee, Klein, Michael A., Bujdoso, Raymond
Publicado em 2007

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6

Por Irvine, Katherine Lucy, Hopkins, Lee Jason, Gangloff, Monique, Bryant, Clare Elizabeth
Publicado em 2013

Architecture of secondary lymphoid tissue in sheep experimentally challenged with scrapie

Por Davies, Marie L, Hopkins, Lee J, Halliday, Sue, Houston, Fiona, Hunter, Nora, McConnell, Ian
Publicado em 2004

Polymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP

Por Yang, Sujeong, Thackray, Alana M., Hopkins, Lee, Monie, Tom P., Burke, David F., Bujdoso, Raymond
Publicado em 2014

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate interleukin-1β production

Por Man, Si Ming, Tourlomousis, Panagiotis, Hopkins, Lee, Monie, Tom P, Fitzgerald, Katherine A., Bryant, Clare E.
Publicado em 2013

Direct Detection of Disease Associated Prions in Brain and Lymphoid Tissue Using Antibodies Recognizing the Extreme N Terminus of PrP(C)

Por Barnard, Geoff, Hopkins, Lee, Moorthie, Sowmiya, Seilly, David, Tonks, Paul, Dabaghian, Reza, Clewley, Jonathan, Coward, John, McConnell, Ian
Publicado em 2007

The Parkinson's disease–associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages

Por Levy, Daniel R., Udgata, Atul, Tourlomousis, Panagiotis, Symmons, Martyn F., Hopkins, Lee J., Bryant, Clare E., Gay, Nicholas J.
Publicado no J Biol Chem (2020)

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

Por Moncrieffe, Martin C., Bollschweiler, Daniel, Li, Bing, Penczek, Pawel A., Hopkins, Lee, Bryant, Clare E., Klenerman, David, Gay, Nicholas J.
Publicado no Structure (2020)

Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella

Por Tourlomousis, Panagiotis, Wright, John A., Bittante, Alessandra S., Hopkins, Lee J., Webster, Steven J., Bryant, Owain J., Mastroeni, Pietro, Maskell, Duncan J., Bryant, Clare E.
Publicado no Nat Microbiol (2020)

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

Por Man, Si Ming, Hopkins, Lee J., Nugent, Eileen, Cox, Susan, Glück, Ivo M., Tourlomousis, Panagiotis, Wright, John A., Cicuta, Pietro, Monie, Tom P., Bryant, Clare E.
Publicado em 2014

Allergens as Immuno-Modulatory Proteins: the cat dander protein Fel d 1 enhances Toll-like receptor activation by lipid ligands

Por Herre, Jurgen, Grönlund, Hans, Brooks, Heather, Hopkins, Lee, Waggoner, Lisa, Murton, Ben, Gangloff, Monique, Opaleye, Olaniyi, Chilvers, Edwin R., Fitzgerald, Kate, Gay, Nick, Monie, Tom, Bryant, Clare
Publicado em 2013

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

Por Hughes, Craig D., Choi, Minee L., Ryten, Mina, Hopkins, Lee, Drews, Anna, Botía, Juan A., Iljina, Maria, Rodrigues, Margarida, Gagliano, Sarah A., Gandhi, Sonia, Bryant, Clare, Klenerman, David
Publicado no Acta Neuropathol (2018)

Correction to: Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

Por Hughes, Craig D., Choi, Minee L., Ryten, Mina, Hopkins, Lee, Drews, Anna, Botía, Juan A., Iljina, Maria, Rodrigues, Margarida, Gagliano, Sarah A., Gandhi, Sonia, Bryant, Clare, Klenerman, David
Publicado no Acta Neuropathol (2018)

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy

Por Jabir, Majid Sakhi, Hopkins, Lee, Ritchie, Neil D., Ullah, Ihsan, Bayes, Hannah K., Li, Dong, Tourlomousis, Panagiotis, Lupton, Alison, Puleston, Daniel, Simon, Anna Katharina, Bryant, Clare, Evans, Thomas J.
Publicado no Autophagy (2015)

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

Por Latty, Sarah Louise, Sakai, Jiro, Hopkins, Lee, Verstak, Brett, Paramo, Teresa, Berglund, Nils A, Cammarota, Eugenia, Cicuta, Pietro, Gay, Nicholas J, Bond, Peter J, Klenerman, David, Bryant, Clare E
Publicado no eLife (2018)