Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrP(C)

Ovine PBMCs (peripheral blood mononuclear cells) express PrP(C) [cellular PrP (prion-related protein)] and have the potential to harbour and release disease-associated forms of PrP during scrapie in sheep. Cell-surface PrP(C) expression by PBMCs, together with plasma PrP(C) levels, may contribute to...

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Bibliographic Details
Main Authors: Thackray, Alana M., Fitzmaurice, Tim J., Hopkins, Lee, Bujdoso, Raymond
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2006
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1652830/
https://ncbi.nlm.nih.gov/pubmed/16881870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060746
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