Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate interleukin-1β production

Nucleotide-binding oligomerization domain-like receptors (NLRs) detect pathogens and danger-associated signals within the cell. Salmonella Typhimurium, an intracellular pathogen, activates caspase-1 required for the processing of the pro-inflammatory cytokines, pro-IL-1β and pro-IL-18, and pyroptosi...

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Main Authors: Man, Si Ming, Tourlomousis, Panagiotis, Hopkins, Lee, Monie, Tom P, Fitzgerald, Katherine A., Bryant, Clare E.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835177/
https://ncbi.nlm.nih.gov/pubmed/24123685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301581
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