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CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

Interleukin-1β (IL-1β) is a proinflammatory cytokine required for host control of bacterial infections, and its production must be tightly regulated to prevent excessive inflammation. Here we show that caspase recruitment domain-containing protein 9 (CARD9), a protein associated with induction of pr...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Pereira, Milton, Tourlomousis, Panagiotis, Wright, John, P. Monie, Tom, Bryant, Clare E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052644/
https://ncbi.nlm.nih.gov/pubmed/27670879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12874
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