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Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella
Pattern recognition receptors (PRRs) expressed in antigen-presenting cells are thought to shape pathogen-specific immunity by inducing secretion of co-stimulatory cytokines during T-cell activation, yet data to support this notion in vivo is surprisingly scarce. Here we show that the cytosolic PRR N...
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| Publicado no: | Nat Microbiol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116404/ https://ncbi.nlm.nih.gov/pubmed/33106673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-00801-y |
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