Prion propagation in vitro: are we there yet?

Por Ryou, Chongsuk, Mays, Charles E.
Publicado em 2008

Plasminogen: A cellular protein cofactor for PrP(Sc) propagation

Por Mays, Charles E, Ryou, Chongsuk
Publicado em 2011

Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source

Por Mays, Charles E., Titlow, William, Seward, Tanya, Telling, Glenn C., Ryou, Chongsuk
Publicado em 2009

The suppression of prion propagation using poly-L-lysine by targeting plasminogen that stimulates prion protein conversion

Por Ryou, Chongsuk, Titlow, William B., Mays, Charles E., Bae, Younsoo, Kim, Sehun
Publicado em 2011

Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics

Por Lyon, Adam, Mays, Charles E., Borriello, Frank, Telling, Glenn C., Soto, Claudio, Pritzkow, Sandra
Publicado no Sci Rep (2019)

Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus

Por Kang, Sang-Gyun, Mays, Charles E., Daude, Nathalie, Yang, Jing, Kar, Satyabrata, Westaway, David
Publicado no Mol Neurobiol (2019)

Modeling amyloid beta and tau pathology in human cerebral organoids

Por Gonzalez, Cesar, Armijo, Enrique, Bravo-Alegria, Javiera, Becerra-Calixto, Andrea, Mays, Charles E., Soto, Claudio
Publicado no Mol Psychiatry (2018)

Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein

Por Stocki, Pawel, Sawicki, Maxime, Mays, Charles E., Hong, Seo Jung, Chapman, Daniel C., Westaway, David, Williams, David B.
Publicado no Mol Biol Cell (2016)

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrP(Sc) Species

Por Mays, Charles E., van der Merwe, Jacques, Kim, Chae, Haldiman, Tracy, McKenzie, Debbie, Safar, Jiri G., Westaway, David
Publicado no J Virol (2015)

Infectious Prions Accumulate to High Levels in Non Proliferative C2C12 Myotubes

Por Herbst, Allen, Banser, Pamela, Velasquez, Camilo Duque, Mays, Charles E., Sim, Valerie L., Westaway, David, Aiken, Judd M., McKenzie, Debbie
Publicado em 2013

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Por Mays, Charles E., Yeom, Jihyun, Kang, Hae-Eun, Bian, Jifeng, Khaychuk, Vadim, Kim, Younghwan, Bartz, Jason C., Telling, Glenn C., Ryou, Chongsuk
Publicado em 2011

CRBL cells: Establishment, characterization and susceptibility to prion infection

Por Mays, Charles E., Kang, Hae-Eun, Kim, Younghwan, Shim, Sung Han, Bang, Ji-Eun, Woo, Hee-Jong, Cho, Youl-Hee, Kim, Jae-Beom, Ryou, Chongsuk
Publicado em 2008

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70)

Por Mays, Charles E., Armijo, Enrique, Morales, Rodrigo, Kramm, Carlos, Flores, Andrea, Tiwari, Anjana, Bian, Jifeng, Telling, Glenn C., Pandita, Tej K., Hunt, Clayton R., Soto, Claudio
Publicado no J Biol Chem (2019)

Prion disease tempo determined by host-dependent substrate reduction

Por Mays, Charles E., Kim, Chae, Haldiman, Tracy, van der Merwe, Jacques, Lau, Agnes, Yang, Jing, Grams, Jennifer, Di Bari, Michele A., Nonno, Romolo, Telling, Glenn C., Kong, Qingzhong, Langeveld, Jan, McKenzie, Debbie, Westaway, David, Safar, Jiri G.
Publicado em 2014

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrP(Sc) Accumulation

Por Westaway, David, Genovesi, Sacha, Daude, Nathalie, Brown, Rebecca, Lau, Agnes, Lee, Inyoul, Mays, Charles E., Coomaraswamy, Janaky, Canine, Brenda, Pitstick, Rose, Herbst, Allen, Yang, Jing, Ko, Kerry W. S., Schmitt-Ulms, Gerold, DeArmond, Stephen J., McKenzie, Debbie, Hood, Leroy, Carlson, George A.
Publicado em 2011

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

Por Lau, Agnes, McDonald, Alex, Daude, Nathalie, Mays, Charles E, Walter, Eric D, Aglietti, Robin, Mercer, Robert CC, Wohlgemuth, Serene, van der Merwe, Jacques, Yang, Jing, Gapeshina, Hristina, Kim, Chae, Grams, Jennifer, Shi, Beipei, Wille, Holger, Balachandran, Aru, Schmitt-Ulms, Gerold, Safar, Jiri G, Millhauser, Glenn L, Westaway, David
Publicado no EMBO Mol Med (2015)

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alle...

Por Mercer, Robert C. C., Daude, Nathalie, Dorosh, Lyudmyla, Fu, Ze-Lin, Mays, Charles E., Gapeshina, Hristina, Wohlgemuth, Serene L., Acevedo-Morantes, Claudia Y., Yang, Jing, Cashman, Neil R., Coulthart, Michael B., Pearson, Dawn M., Joseph, Jeffrey T., Wille, Holger, Safar, Jiri G., Jansen, Gerard H., Stepanova, Maria, Sykes, Brian D., Westaway, David
Publicado no PLoS Pathog (2018)