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Plasminogen: A cellular protein cofactor for PrP(Sc) propagation

The biochemical essence of prion replication is the molecular multiplication of the disease-associated misfolded isoform of prion protein (PrP), termed PrP(Sc), in a nucleic acid-free manner. PrP(Sc) is generated by the protein misfolding process facilitated by conformational conversion of the host-...

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Detalles Bibliográficos
Main Authors: Mays, Charles E, Ryou, Chongsuk
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038002/
https://ncbi.nlm.nih.gov/pubmed/21191173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.1.14460
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