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Plasminogen: A cellular protein cofactor for PrP(Sc) propagation
The biochemical essence of prion replication is the molecular multiplication of the disease-associated misfolded isoform of prion protein (PrP), termed PrP(Sc), in a nucleic acid-free manner. PrP(Sc) is generated by the protein misfolding process facilitated by conformational conversion of the host-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038002/ https://ncbi.nlm.nih.gov/pubmed/21191173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.1.14460 |
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