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PrP assemblies: Spotting the responsible regions in prion propagation
The “protein only” hypothesis states that the key phenomenon in prion pathogenesis is the conversion of the host protein (PrP(C)) into a β-sheet enriched polymeric and pathogenic conformer (PrP(Sc)). However the region of PrP bearing the information for structural transfer is still controversial. In...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166504/ https://ncbi.nlm.nih.gov/pubmed/21788728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16383 |
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