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Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates
Luminescent conjugated polymers (LCPs) interact with ordered protein aggregates and sensitively detect amyloids of many different proteins, suggesting that they may possess antiprion properties. Here, we show that a variety of anionic, cationic, and zwitterionic LCPs reduced the infectivity of prion...
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| Hlavní autoři: | , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365923/ https://ncbi.nlm.nih.gov/pubmed/22493452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355958 |
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