Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates

Luminescent conjugated polymers (LCPs) interact with ordered protein aggregates and sensitively detect amyloids of many different proteins, suggesting that they may possess antiprion properties. Here, we show that a variety of anionic, cationic, and zwitterionic LCPs reduced the infectivity of prion...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Margalith, Ilan, Suter, Carlo, Ballmer, Boris, Schwarz, Petra, Tiberi, Cinzia, Sonati, Tiziana, Falsig, Jeppe, Nyström, Sofie, Hammarström, Per, Åslund, Andreas, Nilsson, K. Peter R., Yam, Alice, Whitters, Eric, Hornemann, Simone, Aguzzi, Adriano
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365923/
https://ncbi.nlm.nih.gov/pubmed/22493452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355958
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky