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Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source
Protein misfolding cyclic amplification (PMCA) is a cell-free assay mimicking the prion replication process. However, constraints affecting PMCA have not been well-defined. Although cellular prion protein (PrP(C)) is required for prion replication, the influence of PrP(C) abundance on PMCA has not b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756978/ https://ncbi.nlm.nih.gov/pubmed/19664595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.163 |
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