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Prion formation, but not clearance, is supported by protein misfolding cyclic amplification
Prion diseases are fatal transmissible neurodegenerative disorders that affect animals including humans. The kinetics of prion infectivity and PrP(Sc) accumulation can differ between prion strains and within a single strain in different tissues. The net accumulation of PrP(Sc) in animals is controll...
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| Pubblicato in: | Prion |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601219/ https://ncbi.nlm.nih.gov/pubmed/25482601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.983759 |
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