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Prion formation, but not clearance, is supported by protein misfolding cyclic amplification
Prion diseases are fatal transmissible neurodegenerative disorders that affect animals including humans. The kinetics of prion infectivity and PrP(Sc) accumulation can differ between prion strains and within a single strain in different tissues. The net accumulation of PrP(Sc) in animals is controll...
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| Gepubliceerd in: | Prion |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601219/ https://ncbi.nlm.nih.gov/pubmed/25482601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.983759 |
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