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Protein Misfolding Cyclic Amplification of Prions

Prions are infectious agents that cause the inevitably fatal transmissible spongiform encephalopathy (TSE) in animals and humans(9,18). The prion protein has two distinct isoforms, the non-infectious host-encoded protein (PrP(C)) and the infectious protein (PrP(Sc)), an abnormally-folded isoform of...

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Podrobná bibliografie
Hlavní autoři: Saunders, Samuel E., Bartz, Jason C., Shikiya, Ronald A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520578/
https://ncbi.nlm.nih.gov/pubmed/23168797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4075
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