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Protein misfolding cyclic amplification of infectious prions

Prions are proteinaceous infectious agents responsible for the transmission of prion diseases. The lack of a procedure for cultivating prions in the laboratory has been a major limitation to the study of the unorthodox nature of this infectious agent and the molecular mechanism by which the normal p...

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Main Authors: Morales, Rodrigo, Duran-Aniotz, Claudia, Diaz-Espinoza, Rodrigo, Camacho, Manuel V, Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049227/
https://ncbi.nlm.nih.gov/pubmed/22743831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.067
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