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High-resolution structure of infectious prion protein: the final frontier

Prions are the proteinaceous infectious agents responsible for the transmission of prion diseases. The main or sole component of prions is the misfolded prion protein (PrP(Sc)), which is able to template the conversion of the host’s natively folded form of the protein (PrP(C)). The detailed mechanis...

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Detalhes bibliográficos
Main Authors: Diaz-Espinoza, Rodrigo, Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049221/
https://ncbi.nlm.nih.gov/pubmed/22472622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2266
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