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Selective Amplification of Classical and Atypical Prions Using Modified Protein Misfolding Cyclic Amplification
With the development of protein misfolding cyclic amplification (PMCA), the topic of faithful propagation of prion strain-specific structures has been constantly debated. Here we show that by subjecting brain material of a synthetic strain consisting of a mixture of self-replicating states to PMCAb,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537030/ https://ncbi.nlm.nih.gov/pubmed/23168413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419531 |
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