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Relationship between conformational stability and amplification efficiency of prions

Recent studies demonstrated that the efficiency, rate and yield of prion amplification in vitro could be substantially improved by supplementing Protein Misfolding Cyclic Amplification (PMCA) with Teflon beads [Gonzalez-Montalban, et al. (2011) PLoS Pathog. 7, e1001277]. Here we employed the new PMC...

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Detalhes bibliográficos
Main Authors: Gonzalez-Montalban, Nuria, Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183828/
https://ncbi.nlm.nih.gov/pubmed/21848309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200950v
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