Strain-dependent profile of misfolded prion protein aggregates

Prions are composed of the misfolded prion protein (PrP(Sc)) organized in a variety of aggregates. An important question in the prion field has been to determine the identity of functional PrP(Sc) aggregates. In this study, we used equilibrium sedimentation in sucrose density gradients to separate P...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Morales, Rodrigo, Hu, Ping Ping, Duran-Aniotz, Claudia, Moda, Fabio, Diaz-Espinoza, Rodrigo, Chen, Baian, Bravo-Alegria, Javiera, Makarava, Natallia, Baskakov, Ilia V., Soto, Claudio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753423/
https://ncbi.nlm.nih.gov/pubmed/26877167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20526
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