Strain-dependent profile of misfolded prion protein aggregates

Prions are composed of the misfolded prion protein (PrP(Sc)) organized in a variety of aggregates. An important question in the prion field has been to determine the identity of functional PrP(Sc) aggregates. In this study, we used equilibrium sedimentation in sucrose density gradients to separate P...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Morales, Rodrigo, Hu, Ping Ping, Duran-Aniotz, Claudia, Moda, Fabio, Diaz-Espinoza, Rodrigo, Chen, Baian, Bravo-Alegria, Javiera, Makarava, Natallia, Baskakov, Ilia V., Soto, Claudio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753423/
https://ncbi.nlm.nih.gov/pubmed/26877167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20526
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