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Independent amplification of co-infected long incubation period low conversion efficiency prion strains

Prion diseases are caused by a misfolded isoform of the prion protein, PrP(Sc). Prion strains are hypothesized to be encoded by strain-specific conformations of PrP(Sc) and prions can interfere with each other when a long-incubation period strain (i.e. blocking strain) inhibits the conversion of a s...

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Pubblicato in:PLoS Pathog
Autori principali: Eckland, Thomas E., Shikiya, Ronald A., Bartz, Jason C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193734/
https://ncbi.nlm.nih.gov/pubmed/30335854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007323
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