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Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism

While neuropathological features that define prion strains include spongiform degeneration and deposition patterns of PrP(Sc), the underlying mechanism for the strain-specific differences in PrP(Sc) targeting is not known. To investigate prion strain targeting, we inoculated hamsters in the sciatic...

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Detalhes bibliográficos
Main Authors: Ayers, Jacob I., Kincaid, Anthony E., Bartz, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612296/
https://ncbi.nlm.nih.gov/pubmed/18971281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01745-08
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