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Efficient interspecies transmission of synthetic prions
Prions are comprised solely of PrP(Sc), the misfolded self-propagating conformation of the cellular protein, PrP(C). Synthetic prions are generated in vitro from minimal components and cause bona fide prion disease in animals. It is unknown, however, if synthetic prions can cross the species barrier...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8312972/ https://ncbi.nlm.nih.gov/pubmed/34260664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009765 |
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