Molecular pathogenesis of sporadic prion diseases in man

Por Safar, Jiri G.
Publicado em 2012

Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease

Por Cohen, Mark, Appleby, Brian, Safar, Jiri G.
Publicado no Prion (2016)

Search for a Prion-Specific Nucleic Acid

Por Safar, Jiri G., Kellings, Klaus, Serban, Ana, Groth, Darlene, Cleaver, James E., Prusiner, Stanley B., Riesner, Detlev
Publicado em 2005

Protease-Sensitive Conformers in Broad Spectrum of Distinct PrP(Sc) Structures in Sporadic Creutzfeldt-Jakob Disease Are Indicator of Progression Rate

Por Kim, Chae, Haldiman, Tracy, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Sy, Man-Sun, Cohen, Mark, Safar, Jiri G.
Publicado em 2011

Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein

Por Wille, Holger, Shanmugam, Maheswaran, Murugesu, Muralee, Ollesch, Julian, Stubbs, Gerald, Long, Jeffrey R., Safar, Jiri G., Prusiner, Stanley B.
Publicado em 2009

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrP(Sc) Species

Por Mays, Charles E., van der Merwe, Jacques, Kim, Chae, Haldiman, Tracy, McKenzie, Debbie, Safar, Jiri G., Westaway, David
Publicado no J Virol (2015)

Transmission and Detection of Prions in Feces

Por Safar, Jiri G., Lessard, Pierre, Tamgüney, Gültekin, Freyman, Yevgeniy, Deering, Camille, Letessier, Frederic, DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2008

Conserved properties of human and bovine prion strains on transmission to guinea pigs

Por Safar, Jiri G., Giles, Kurt, Lessard, Pierre, Letessier, Frederic, Patel, Smita, Serban, Ana, DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2011

Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease

Por Choi, Ed M., Geschwind, Michael D., Deering, Camille, Pomeroy, Kristen, Kuo, Amy, Miller, Bruce L., Safar, Jiri G., Prusiner, Stanley B.
Publicado em 2009

Mutant PrP(Sc) Conformers Induced by a Synthetic Peptide and Several Prion Strains

Por Tremblay, Patrick, Ball, Haydn L., Kaneko, Kiyotoshi, Groth, Darlene, Hegde, Ramanujan S., Cohen, Fred E., DeArmond, Stephen J., Prusiner, Stanley B., Safar, Jiri G.
Publicado em 2004

Structural Determinants of Phenotypic Diversity and Replication Rate of Human Prions

Por Safar, Jiri G., Xiao, Xiangzhu, Kabir, Mohammad E., Chen, Shugui, Kim, Chae, Haldiman, Tracy, Cohen, Yvonne, Chen, Wei, Cohen, Mark L., Surewicz, Witold K.
Publicado no PLoS Pathog (2015)

Co-existence of Distinct Prion Types Enables Conformational Evolution of Human PrP(Sc) by Competitive Selection

Por Haldiman, Tracy, Kim, Chae, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Qing, Liuting, Cohen, Mark L., Langeveld, Jan, Telling, Glenn C., Kong, Qingzhong, Safar, Jiri G.
Publicado em 2013

Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Correlation of Histopathology and MRI in Prion Disease

Por Mente, Karin P., O’Donnell, James K., Jones, Stephen E., Cohen, Mark L., Thompson, Nicolas R., Bizzi, Alberto, Gambetti, Pierluigi, Safar, Jiri G., Appleby, Brian S.
Publicado no Alzheimer Dis Assoc Disord (2017)

Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt–Jakob disease: its effect on the phenotype and prion-type characteristics

Por Cali, Ignazio, Castellani, Rudolph, Alshekhlee, Amer, Cohen, Yvonne, Blevins, Janis, Yuan, Jue, Langeveld, Jan P. M., Parchi, Piero, Safar, Jiri G., Zou, Wen-Quan, Gambetti, Pierluigi
Publicado em 2009

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)

Por Kim, Chae, Haldiman, Tracy, Surewicz, Krystyna, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Sy, Man-Sun, Cohen, Mark, Kong, Qingzhong, Telling, Glenn C., Surewicz, Witold K., Safar, Jiri G.
Publicado em 2012

Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type

Por Cracco, Laura, Notari, Silvio, Cali, Ignazio, Sy, Man-Sun, Chen, Shu G., Cohen, Mark L., Ghetti, Bernardino, Appleby, Brian S., Zou, Wen-Quan, Caughey, Byron, Safar, Jiri G., Gambetti, Pierluigi
Publicado no Sci Rep (2017)

Proteomic Differences in Amyloid Plaques in Rapidly Progressive and Sporadic Alzheimer’s Disease

Por Drummond, Eleanor, Nayak, Shruti, Faustin, Arline, Pires, Geoffrey, Hickman, Richard, Askenazi, Manor, Cohen, Mark, Haldiman, Tracy, Kim, Chae, Han, Xiaoxia, Shao, Yongzhao, Safar, Jiri G., Ueberheide, Beatrix, Wisniewski, Thomas
Publicado no Acta Neuropathol (2017)

Diagnosis of human prion disease

Por Safar, Jiri G., Geschwind, Michael D., Deering, Camille, Didorenko, Svetlana, Sattavat, Mamta, Sanchez, Henry, Serban, Ana, Vey, Martin, Baron, Henry, Giles, Kurt, Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2005

Inactivation of Prions by Acidic Sodium Dodecyl Sulfate

Por Peretz, David, Supattapone, Surachai, Giles, Kurt, Vergara, Julie, Freyman, Yevgeniy, Lessard, Pierre, Safar, Jiri G., Glidden, David V., McCulloch, Charles, Nguyen, Hoang-Oanh B., Scott, Michael, DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2006

Human prions and plasma lipoproteins

Por Safar, Jiri G., Wille, Holger, Geschwind, Michael D., Deering, Camille, Latawiec, Diane, Serban, Ana, King, David J., Legname, Giuseppe, Weisgraber, Karl H., Mahley, Robert W., Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2006