Diagnosis of human prion disease

With the discovery of the prion protein (PrP), immunodiagnostic procedures were applied to diagnose Creutzfeldt–Jakob disease (CJD). Before development of the conformation-dependent immunoassay (CDI), all immunoassays for the disease-causing PrP isoform (PrP(Sc)) used limited proteolysis to digest t...

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Detalhes bibliográficos
Main Authors: Safar, Jiri G., Geschwind, Michael D., Deering, Camille, Didorenko, Svetlana, Sattavat, Mamta, Sanchez, Henry, Serban, Ana, Vey, Martin, Baron, Henry, Giles, Kurt, Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552933/
https://ncbi.nlm.nih.gov/pubmed/15741275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409651102
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