Transmission of Elk and Deer Prions to Transgenic Mice

Chronic wasting disease (CWD) is a fatal prion disease in deer and elk. Unique among the prion diseases, it is transmitted among captive and free-ranging animals. To facilitate studies of the biology of CWD prions, we generated five lines of transgenic (Tg) mice expressing prion protein (PrP) from R...

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Hlavní autoři: Tamgüney, Gültekin, Giles, Kurt, Bouzamondo-Bernstein, Essia, Bosque, Patrick J., Miller, Michael W., Safar, Jiri, DeArmond, Stephen J., Prusiner, Stanley B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563923/
https://ncbi.nlm.nih.gov/pubmed/16940522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00098-06
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