Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein

Chronic wasting disease (CWD) is a transmissible, fatal prion disease of cervids and is largely confined to North America. The origin of CWD continues to pose a conundrum: does the disease arise spontaneously or result from some other naturally occurring reservoir? To address whether prions from she...

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Main Authors: Tamgüney, Gültekin, Miller, Michael W., Giles, Kurt, Lemus, Azucena, Glidden, David V., DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2009
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804060/
https://ncbi.nlm.nih.gov/pubmed/19264659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.007500-0
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