Diagnosis of human prion disease

With the discovery of the prion protein (PrP), immunodiagnostic procedures were applied to diagnose Creutzfeldt–Jakob disease (CJD). Before development of the conformation-dependent immunoassay (CDI), all immunoassays for the disease-causing PrP isoform (PrP(Sc)) used limited proteolysis to digest t...

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Bibliografiske detaljer
Main Authors:	Safar, Jiri G., Geschwind, Michael D., Deering, Camille, Didorenko, Svetlana, Sattavat, Mamta, Sanchez, Henry, Serban, Ana, Vey, Martin, Baron, Henry, Giles, Kurt, Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2005
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC552933/ https://ncbi.nlm.nih.gov/pubmed/15741275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409651102
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Diagnosis of human prion disease

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