Diagnosis of human prion disease

With the discovery of the prion protein (PrP), immunodiagnostic procedures were applied to diagnose Creutzfeldt–Jakob disease (CJD). Before development of the conformation-dependent immunoassay (CDI), all immunoassays for the disease-causing PrP isoform (PrP(Sc)) used limited proteolysis to digest t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Safar, Jiri G., Geschwind, Michael D., Deering, Camille, Didorenko, Svetlana, Sattavat, Mamta, Sanchez, Henry, Serban, Ana, Vey, Martin, Baron, Henry, Giles, Kurt, Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15741275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409651102
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