Diagnosis of human prion disease

With the discovery of the prion protein (PrP), immunodiagnostic procedures were applied to diagnose Creutzfeldt–Jakob disease (CJD). Before development of the conformation-dependent immunoassay (CDI), all immunoassays for the disease-causing PrP isoform (PrP(Sc)) used limited proteolysis to digest t...

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Hlavní autoři: Safar, Jiri G., Geschwind, Michael D., Deering, Camille, Didorenko, Svetlana, Sattavat, Mamta, Sanchez, Henry, Serban, Ana, Vey, Martin, Baron, Henry, Giles, Kurt, Miller, Bruce L., DeArmond, Stephen J., Prusiner, Stanley B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC552933/
https://ncbi.nlm.nih.gov/pubmed/15741275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409651102
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