Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors

od Furtek, Steffanie L., Matheson, Christopher J., Backos, Donald S., Reigan, Philip
izdano v Oncotarget (2016)

Development of potent pyrazolopyrimidinone-based WEE1 inhibitors with limited single-agent cytotoxicity for cancer therapy

od Matheson, Christopher J., Casalvieri, Kimberly A, Backos, Donald S., Reigan, Philip
izdano v ChemMedChem (2018)

Molecular docking of substituted pteridinones and pyrimidines to the ATP-binding site of the N-terminal domain of RSK2 and associated MM/GBSA and molecular field datasets

od Casalvieri, Kimberly A., Matheson, Christopher J., Backos, Donald S., Reigan, Philip
izdano v Data Brief (2020)

Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors

od Matheson, Christopher J., Casalvieri, Kimberly A., Backos, Donald S., Minhajuddin, Mohammed, Jordan, Craig T., Reigan, Philip
izdano v Eur J Med Chem (2020)

RSK3 – A Regulator of Pathological Cardiac Remodeling

od Martinez, Eliana C., Passariello, Catherine L., Li, Jinliang, Matheson, Christopher J., Dodge-Kafka, Kimberly, Reigan, Philip, Kapiloff, Michael S.
izdano v IUBMB Life (2015)

Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors

od Xiong, Weipeng, Matheson, Christopher J., Xu, Mei, Backos, Donald S., Mills, Taylor S., Salian-Mehta, Smita, Kiseljak-Vassiliades, Katja, Reigan, Philip, Wierman, Margaret E.
izdano v Mol Cancer Ther (2015)

A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain

od Tabakoff, Boris, Ren, Wenhua, Vanderlinden, Lauren, Snell, Lawrence D., Matheson, Christopher J., Wang, Ze-Jun, Levinson, Rock, Smothers, C. Thetford, Woodward, John J., Honse, Yumiko, Lovinger, David, Rush, Anthony M., Sather, William A., Gustafson, Daniel L., Hoffman, Paula L.
izdano v Eur J Pharmacol (2016)

2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase

od Matheson, Christopher J., Coxon, Christopher R., Bayliss, Richard, Boxall, Kathy, Carbain, Benoit, Fry, Andrew M., Hardcastle, Ian R., Harnor, Suzannah J., Mas-Droux, Corine, Newell, David R., Richards, Mark W., Sivaprakasam, Mangaleswaran, Turner, David, Griffin, Roger J., Golding, Bernard T., Cano, Céline
izdano v RSC Med Chem (2020)

Structure-guided design of purine-based probes for selective Nek2 inhibition

od Coxon, Christopher R., Wong, Christopher, Bayliss, Richard, Boxall, Kathy, Carr, Katherine H., Fry, Andrew M., Hardcastle, Ian R., Matheson, Christopher J., Newell, David R., Sivaprakasam, Mangaleswaran, Thomas, Huw, Turner, David, Yeoh, Sharon, Wang, Lan Z., Griffin, Roger J., Golding, Bernard T., Cano, Céline
izdano v Oncotarget (2016)

Allosteric Inhibitors of the Eya2 Phosphatase Are Selective and Inhibit Eya2-mediated Cell Migration

od Krueger, Aaron B., Drasin, David J., Lea, Wendy A., Patrick, Aaron N., Patnaik, Samarjit, Backos, Donald S., Matheson, Christopher J., Hu, Xin, Barnaeva, Elena, Holliday, Michael J., Blevins, Melanie A., Robin, Tyler P., Eisenmesser, Elan Z., Ferrer, Marc, Simeonov, Anton, Southall, Noel, Reigan, Philip, Marugan, Juan, Ford, Heide L., Zhao, Rui
Izdano 2014

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

od Coxon, Christopher R., Anscombe, Elizabeth, Harnor, Suzannah J., Martin, Mathew P., Carbain, Benoit, Golding, Bernard T., Hardcastle, Ian R., Harlow, Lisa K., Korolchuk, Svitlana, Matheson, Christopher J., Newell, David R., Noble, Martin E. M., Sivaprakasam, Mangaleswaran, Tudhope, Susan J., Turner, David M., Wang, Lan Z., Wedge, Stephen R., Wong, Christopher, Griffin, Roger J., Endicott, Jane A., Cano, Céline
izdano v J Med Chem (2016)