Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: Possible role of the prolonged half-life of the immunogen

Por Zhang, Mei-Yun, Wang, Yanping, Mankowski, Marie K., Ptak, Roger G., Dimitrov, Dimiter S.
Publicado em 2008

Structure–Activity Relationships of a Novel Capsid Targeted Inhibitor of HIV-1 Replication

Por Kortagere, Sandhya, Xu, Jimmy P., Mankowski, Marie K., Ptak, Roger G., Cocklin, Simon
Publicado no J Chem Inf Model (2014)

Highly Potent Chimeric Inhibitors Targeting Two Steps of HIV Cell Entry

Por Zhao, Bo, Mankowski, Marie K., Snyder, Beth A., Ptak, Roger G., LiWang, Patricia J.
Publicado em 2011

Evaluation of PD 404,182 as an Anti-HIV and Anti-Herpes Simplex Virus Microbicide

Por Chamoun-Emanuelli, Ana M., Bobardt, Michael, Moncla, Bernard, Mankowski, Marie K., Ptak, Roger G., Gallay, Philippe, Chen, Zhilei
Publicado em 2014

Potent Strategy To Inhibit HIV-1 by Binding both gp120 and gp41

Por Kagiampakis, Ioannis, Gharibi, Arbi, Mankowski, Marie K., Snyder, Beth A., Ptak, Roger G., Alatas, Kristabelle, LiWang, Patricia J.
Publicado em 2011

Structure–Activity Relationship Studies of Indole-Based Compounds as Small Molecule HIV-1 Fusion Inhibitors Targeting Glycoprotein 41

Por Zhou, Guangyan, Sofiyev, Vladimir, Kaur, Hardeep, Snyder, Beth A., Mankowski, Marie K., Hogan, Priscilla A., Ptak, Roger G., Gochin, Miriam
Publicado em 2014

Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein

Por Zentner, Isaac, Sierra, Luz-Jeannette, Maciunas, Lina, Vinnik, Andrei, Fedichev, Peter, Mankowski, Marie K., Ptak, Roger G., Martín-García, Julio, Cocklin, Simon
Publicado em 2012

Redoxal, an Inhibitor of De Novo Pyrimidine Biosynthesis, Augments APOBEC3G Antiviral Activity Against Human Immunodeficiency Virus Type 1

Por Pery, Erez, Sheehy, Ann, Nebane, N. Miranda, Misra, Vikas, Mankowski, Marie K., Rasmussen, Lynn, White, E. Lucile, Ptak, Roger G., Gabuzda, Dana
Publicado no Virology (2015)

A Novel Anti-HIV Active Integrase Inhibitor with a Favorable In Vitro Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Metabolism Profile

Por Okello, Maurice O., Mishra, Sanjay, Nishonov, Malik, Mankowski, Marie K., Russell, Julie D., Wei, Jiayi, Hogan, Priscilla A., Ptak, Roger G., Nair, Vasu
Publicado em 2013

Critical Design Features of Phenyl Carboxylate-Containing Polymer Microbicides

Por Rando, Robert F., Obara, Sakae, Osterling, Mark C., Mankowski, Marie, Miller, Shendra R., Ferguson, Mary L., Krebs, Fred C., Wigdahl, Brian, Labib, Mohamed, Kokubo, Hiroyasu
Publicado em 2006

Development of Hexadecyloxypropyl Tenofovir (CMX157) for Treatment of Infection Caused by Wild-Type and Nucleoside/Nucleotide-Resistant HIV

Por Lanier, E. Randall, Ptak, Roger G., Lampert, Bernhard M., Keilholz, Laurie, Hartman, Tracy, Buckheit, Robert W., Mankowski, Marie K., Osterling, Mark C., Almond, Merrick R., Painter, George R.
Publicado em 2010

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

Por Tuyishime, Marina, Danish, Matt, Princiotto, Amy, Mankowski, Marie K., Lawrence, Rae, Lombart, Henry-Georges, Esikov, Kirill, Berniac, Joel, Liang, Kuang, Jingjing, Ji, Ptak, Roger G., Madani, Navid, Cocklin, Simon
Publicado no Bioorg Med Chem Lett (2014)

Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm

Por Lackman-Smith, Carol S, Snyder, Beth A, Marotte, Katherine M, Osterling, Mark C, Mankowski, Marie K, Jones, Maureen, Nieves-Duran, Lourdes, Richardson-Harman, Nicola, Cummins, James E, Sanders-Beer, Brigitte E
Publicado em 2010

Identification of a Novel HIV-1 Inhibitor Targeting Vif-dependent Degradation of Human APOBEC3G Protein

Por Pery, Erez, Sheehy, Ann, Nebane, N. Miranda, Brazier, Andrew Jay, Misra, Vikas, Rajendran, Kottampatty S., Buhrlage, Sara J., Mankowski, Marie K., Rasmussen, Lynn, White, E. Lucile, Ptak, Roger G., Gabuzda, Dana
Publicado no J Biol Chem (2015)

Development of a Comprehensive Human Immunodeficiency Virus Type 1 Screening Algorithm for Discovery and Preclinical Testing of Topical Microbicides

Por Lackman-Smith, Carol, Osterling, Clay, Luckenbaugh, Katherine, Mankowski, Marie, Snyder, Beth, Lewis, Gareth, Paull, Jeremy, Profy, Albert, Ptak, Roger G., Buckheit, Robert W., Watson, Karen M., Cummins, James E., Sanders-Beer, Brigitte E.
Publicado em 2008

An Analog of Camptothecin Inactive Against Topoisomerase I is Broadly Neutralizing of HIV-1 Through Inhibition of Vif-Dependent APOBEC3G Degradation

Por Bennett, Ryan P., Stewart, Ryan A., Hogan, Priscilla A., Ptak, Roger G., Mankowski, Marie K., Hartman, Tracy L., Buckheit, Robert W., Snyder, Beth A., Salter, Jason D., Morales, Guillermo A., Smith, Harold C.
Publicado no Antiviral Res (2016)

Albumin-conjugated C34 Peptide HIV-1 Fusion Inhibitor: EQUIPOTENT TO C34 AND T-20 IN VITRO WITH SUSTAINED ACTIVITY IN SCID-HU THY/LIV MICE

Por Stoddart, Cheryl A., Nault, Geneviève, Galkina, Sofiya A., Thibaudeau, Karen, Bakis, Peter, Bousquet-Gagnon, Nathalie, Robitaille, Martin, Bellomo, Maryanne, Paradis, Véronique, Liscourt, Patricia, Lobach, Alexandra, Rivard, Marie-Ève, Ptak, Roger G., Mankowski, Marie K., Bridon, Dominique, Quraishi, Omar
Publicado em 2008

Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid

Por Kortagere, Sandhya, Madani, Navid, Mankowski, Marie K., Schön, Arne, Zentner, Isaac, Swaminathan, Gokul, Princiotto, Amy, Anthony, Kevin, Oza, Apara, Sierra, Luz-Jeannette, Passic, Shendra R., Wang, Xiaozhao, Jones, David M., Stavale, Eric, Krebs, Fred C., Martín-García, Julio, Freire, Ernesto, Ptak, Roger G., Sodroski, Joseph, Cocklin, Simon, Smith, Amos B.
Publicado em 2012

Abasic Phosphorothioate Oligomers Inhibit HIV-1 Reverse Transcription and Block Virus Transmission across Polarized Ectocervical Organ Cultures

Por Fraietta, Joseph A., Mueller, Yvonne M., Lozenski, Karissa L., Ratner, Deena, Boesteanu, Alina C., Hancock, Aidan S., Lackman-Smith, Carol, Zentner, Isaac J., Chaiken, Irwin M., Chung, Suhman, LeGrice, Stuart F. J., Snyder, Beth A., Mankowski, Marie K., Jones, Natalie M., Hope, Jennifer L., Gupta, Phalguni, Anderson, Sharon H., Wigdahl, Brian, Katsikis, Peter D.
Publicado no Antimicrob Agents Chemother (2014)

In Vitro Preclinical Testing of Nonoxynol-9 as Potential Anti-Human Immunodeficiency Virus Microbicide: a Retrospective Analysis of Results from Five Laboratories

Por Beer, Brigitte E., Doncel, Gustavo F., Krebs, Fred C., Shattock, Robin J., Fletcher, Patricia S., Buckheit, Robert W., Watson, Karen, Dezzutti, Charlene S., Cummins, James E., Bromley, Ena, Richardson-Harman, Nicola, Pallansch, Luke A., Lackman-Smith, Carol, Osterling, Clay, Mankowski, Marie, Miller, Shendra R., Catalone, Bradley J., Welsh, Patricia A., Howett, Mary K., Wigdahl, Brian, Turpin, Jim A., Reichelderfer, Patricia
Publicado em 2006