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Structure–Activity Relationship Studies of Indole-Based Compounds as Small Molecule HIV-1 Fusion Inhibitors Targeting Glycoprotein 41
[Image: see text] We previously described indole-containing compounds with the potential to inhibit HIV-1 fusion by targeting the hydrophobic pocket of transmembrane glycoprotein gp41. Here we report optimization and structure–activity relationship studies on the basic scaffold, defining the role of...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2014
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216203/ https://ncbi.nlm.nih.gov/pubmed/24856833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500344y |
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