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Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 glycoprotein-41

Non-peptide inhibition of fusion remains an important goal in anti-HIV research, due to its potential for low cost prophylaxis or prevention of cell–cell transmission of the virus. We report here on a series of indole compounds that have been identified as fusion inhibitors of gp41 through a structu...

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Detalhes bibliográficos
Main Authors: Zhou, Guangyan, Wu, Dong, Snyder, Beth, Ptak, Roger G., Kaur, Harmeet, Gochin, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234170/
https://ncbi.nlm.nih.gov/pubmed/21928824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200791z
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