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Highly Potent Chimeric Inhibitors Targeting Two Steps of HIV Cell Entry
Blocking HIV-1 cell entry has long been a major goal of anti-HIV drug development. Here, we report a successful design of two highly potent chimeric HIV entry inhibitors composed of one CCR5-targeting RANTES (regulated on activation normal T cell expressed and secreted) variant (5P12-RANTES or 5P14-...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151080/ https://ncbi.nlm.nih.gov/pubmed/21659523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234799 |
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