GEFs: Dual regulation of Rac1 signaling

par Marei, Hadir, Malliri, Angeliki
Publié dans Small GTPases (2016)

Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

par Marei, Hadir, Malliri, Angeliki
Publié dans Small GTPases (2016)

Centrosome separation; a careful balancing act

par Whalley, Helen J, Malliri, Angeliki
Publié dans Cell Cycle (2015)

Deregulation of Rho GTPases in cancer

par Porter, Andrew P., Papaioannou, Alexandra, Malliri, Angeliki
Publié dans Small GTPases (2016)

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors

par Marei, Hadir, Carpy, Alejandro, Macek, Boris, Malliri, Angeliki
Publié dans Cell Cycle (2016)

The diverse roles of Rac signaling in tumorigenesis

par Mack, Natalie A, Whalley, Helen J, Castillo-Lluva, Sonia, Malliri, Angeliki
Publié 2011

The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia

par Porter, Andrew P., White, Gavin R. M., Mack, Natalie A., Malliri, Angeliki
Publié dans J Cell Sci (2019)

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

par Rooney, Claire, White, Gavin, Nazgiewicz, Alicja, Woodcock, Simon A, Anderson, Kurt I, Ballestrem, Christoph, Malliri, Angeliki
Publié 2010

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

par Marei, Hadir, Carpy, Alejandro, Woroniuk, Anna, Vennin, Claire, White, Gavin, Timpson, Paul, Macek, Boris, Malliri, Angeliki
Publié dans Nat Commun (2016)

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

par Whalley, Helen J., Porter, Andrew P., Diamantopoulou, Zoi, White, Gavin R. M., Castañeda-Saucedo, Eduardo, Malliri, Angeliki
Publié dans Nat Commun (2015)

The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels

par Porter, Andrew P., Reed, Hannah, White, Gavin R. M., Ogg, Erinn-Lee, Whalley, Helen J., Malliri, Angeliki
Publié dans J Cell Sci (2021)

The Transcription Factor AP-1 Is Required for EGF-induced Activation of Rho-like GTPases, Cytoskeletal Rearrangements, Motility, and In Vitro Invasion of A431 Cells

par Malliri, Angeliki, Symons, Marc, Hennigan, Robert F., Hurlstone, Adam F.L., Lamb, Richard F., Wheeler, Tricia, Ozanne, Bradford W.
Publié 1998

SUMOylation of the GTPase Rac1 is required for optimal cell migration

par Castillo-Lluva, Sonia, Tatham, Michael H., Jones, Richard C., Jaffray, Ellis G., Edmondson, Ricky D., Hay, Ronald T., Malliri, Angeliki
Publié 2010

Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

par Woodcock, Simon A., Rushton, Helen J., Castañeda-Saucedo, Eduardo, Myant, Kevin, White, Gavin R.M., Blyth, Karen, Sansom, Owen J., Malliri, Angeliki
Publié 2010

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion

par Vaughan, Lynsey, Tan, Chong-Teik, Chapman, Anna, Nonaka, Daisuke, Mack, Natalie A., Smith, Duncan, Booton, Richard, Hurlstone, Adam F.L., Malliri, Angeliki
Publié dans Cell Rep (2014)

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity

par Mack, Natalie A., Porter, Andrew P., Whalley, Helen J., Schwarz, Juliane P., Jones, Richard C., Syed, Azharuddin Sajid, Bjartell, Anders, Anderson, Kurt I., Malliri, Angeliki
Publié 2012

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap

par Woroniuk, Anna, Porter, Andrew, White, Gavin, Newman, Daniel T., Diamantopoulou, Zoi, Waring, Thomas, Rooney, Claire, Strathdee, Douglas, Marston, Daniel J., Hahn, Klaus M., Sansom, Owen J., Zech, Tobias, Malliri, Angeliki
Publié dans Nat Commun (2018)

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

par Daugaard, Mads, Nitsch, Roberto, Razaghi, Babak, McDonald, Lindsay, Jarrar, Ameer, Torrino, Stéphanie, Castillo-Lluva, Sonia, Rotblat, Barak, Li, Liheng, Malliri, Angeliki, Lemichez, Emmanuel, Mettouchi, Amel, Berman, Jason N., Penninger, Josef M., Sorensen, Poul H.
Publié 2013

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

par Diamantopoulou, Zoi, White, Gavin, Fadlullah, Muhammad Z.H., Dreger, Marcel, Pickering, Karen, Maltas, Joe, Ashton, Garry, MacLeod, Ruth, Baillie, George S., Kouskoff, Valerie, Lacaud, Georges, Murray, Graeme I., Sansom, Owen J., Hurlstone, Adam F.L., Malliri, Angeliki
Publié dans Cancer Cell (2017)

Ultraviolet light-induced collagen degradation inhibits melanoma invasion

par Budden, Timothy, Gaudy-Marqueste, Caroline, Porter, Andrew, Kay, Emily, Gurung, Shilpa, Earnshaw, Charles H., Roeck, Katharina, Craig, Sarah, Traves, Víctor, Krutmann, Jean, Muller, Patricia, Motta, Luisa, Zanivan, Sara, Malliri, Angeliki, Furney, Simon J., Nagore, Eduardo, Virós, Amaya
Publié dans Nat Commun (2021)