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Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

Abnormal Rac1 signaling is linked to a number of debilitating human diseases, including cancer, cardiovascular diseases and neurodegenerative disorders. As such, Rac1 represents an attractive therapeutic target, yet the search for effective Rac1 inhibitors is still underway. Given the adverse effect...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Marei, Hadir, Malliri, Angeliki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584733/
https://ncbi.nlm.nih.gov/pubmed/27442895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1211398
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