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GEFs: Dual regulation of Rac1 signaling
GEFs play a critical role in regulating Rac1 signaling. They serve as signaling nodes converting upstream signals into downstream Rac1-driven cellular responses. Through associating with membrane-bound Rac1, GEFs facilitate the exchange of GDP for GTP, thereby activating Rac1. As a result, Rac1 unde...
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| Published in: | Small GTPases |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464116/ https://ncbi.nlm.nih.gov/pubmed/27314616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1202635 |
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