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Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

Abnormal Rac1 signaling is linked to a number of debilitating human diseases, including cancer, cardiovascular diseases and neurodegenerative disorders. As such, Rac1 represents an attractive therapeutic target, yet the search for effective Rac1 inhibitors is still underway. Given the adverse effect...

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Dettagli Bibliografici
Pubblicato in:Small GTPases
Autori principali: Marei, Hadir, Malliri, Angeliki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584733/
https://ncbi.nlm.nih.gov/pubmed/27442895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1211398
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